Role of active nanoliposomes in the surface and bulk mechanical properties of hybrid hydrogels
| Autor: | Laura Sánchez-González, Stéphane Desobry, Grégory Francius, Elmira Arab-Tehrany, J. Bacharouch, Ali Tamayol, R. Kadri, João F. Mano, Michel Linder, Cyril J.F. Kahn, G. Ben Messaoud, Kamil Elkhoury |
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| Přispěvatelé: | Laboratoire d'Ingénierie des Biomolécules (LIBio), Université de Lorraine (UL), Department of Mechanical and Materials Engineering [University of Nebraska–Lincoln], University of Nebraska [Lincoln], University of Nebraska System-University of Nebraska System, Laboratoire de Chimie Physique et Microbiologie pour les Matériaux et l'Environnement (LCPME), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Center for Research in Ceramic and Composite Materials (CICECO), Universidade de Aveiro, Institut de Chimie du CNRS (INC)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
food.ingredient
Materials science [SDV.BIO]Life Sciences [q-bio]/Biotechnology Biomedical Engineering Bioengineering macromolecular substances 02 engineering and technology 010402 general chemistry complex mixtures 01 natural sciences Gelatin Biomaterials Composite hydrogels food Tissue engineering Full Length Article Highly porous [CHIM]Chemical Sciences Interpenetrating polymer network [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials lcsh:QH301-705.5 Molecular Biology ComputingMilieux_MISCELLANEOUS GelMA lcsh:R5-920 Liposome Alginate technology industry and agriculture IPN hydrogels [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph] Cell Biology 021001 nanoscience & nanotechnology 3. Good health 0104 chemical sciences lcsh:Biology (General) Chemical engineering Liposomes Self-healing hydrogels Drug delivery lcsh:Medicine (General) 0210 nano-technology Nanofunctionalization Biotechnology |
| Zdroj: | Materials Today Bio Materials Today Bio, Elsevier, 2020, 6, pp.100046. ⟨10.1016/j.mtbio.2020.100046⟩ Materials Today Bio, Elsevier, 2020, 6 (10), pp.100046. ⟨10.1016/j.mtbio.2020.100046⟩ Materials Today Bio, Vol 6, Iss, Pp 100046-(2020) |
| ISSN: | 2590-0064 |
| DOI: | 10.1016/j.mtbio.2020.100046⟩ |
| Popis: | Nanoliposomes are widely used as delivery vehicles for active compounds. Nanoliposomes from rapeseed phospholipids were incorporated into interpenetrating polymer network hydrogels of gelatin methacryloyl and alginate. The multiscale physicochemical properties of the hydrogels are studied both on the surface and through the thickness of the 3D network. The obtained composite hydrogels exhibited strong mechanical properties and a highly porous surface. The blend ratio, as well as the concentration of nanoliposomes, affects the properties of the hydrogels. Nanofunctionalized hydrogels induced keratinocyte growth. These advantageous characteristics may open up many applications of the developed hydrogels in drug delivery and tissue engineering. Graphical abstract Image 1 |
| Databáze: | OpenAIRE |
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