Post-implantation syndrome following endovascular abdominal aortic aneurysm repair: preliminary data
| Autor: | Eleni Arnaoutoglou, George K. Papadopoulos, Nektario Papa, George Kouvelos, Nikolaos Kolaitis, Haralampos J. Milionis, Miltiadis Matsagkas, Anestis Mavridis |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Systemic Inflammatory Response Syndrome/blood/*etiology/immunology medicine.medical_treatment Pilot Projects Blood Vessel Prosthesis Implantation/*adverse effects Endovascular aneurysm repair Blood Vessel Prosthesis Implantation Aortic aneurysm Humans Medicine Prospective Studies Prospective cohort study Aged Aged 80 and over Chi-Square Distribution Greece medicine.diagnostic_test biology business.industry Endovascular Procedures C-reactive protein Complete blood count Length of Stay Middle Aged medicine.disease Endovascular Procedures/*adverse effects Systemic Inflammatory Response Syndrome Abdominal aortic aneurysm Surgery Treatment Outcome Inflammation Mediators/blood Aortic Aneurysm Abdominal/*surgery biology.protein Female Inflammation Mediators Cardiology and Cardiovascular Medicine business Complication Aortic Aneurysm Abdominal Abdominal surgery |
| Zdroj: | Interactive CardioVascular and Thoracic Surgery. 12:609-614 |
| ISSN: | 1569-9293 |
| DOI: | 10.1510/icvts.2010.256784 |
| Popis: | OBJECTIVES: Endovascular aneurysm repair (EVAR), may elicit an unexpected systemic inflammatory response, which has been named post-implantation syndrome (PIS). The aim of this study was to prospectively evaluate the association of PIS with clinical and laboratory parameters in patients who underwent EVAR for abdominal aortic aneurysms (AAA). METHODS: Forty consecutive patients who underwent EVAR for AAA were studied. Complete blood count, fibrinogen, high sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, IL-1, tumor necrosis factor-alpha were determined before and after surgery. Several parameters regarding the operation, as well as the hospitalization days were recorded. RESULTS: PIS was diagnosed in 35% of the patients. Patients with PIS showed significant greater changes of inflammation marker levels, including hs-CRP and IL-6, as compared with the non-PIS group. PIS was associated with longer hospitalization. CONCLUSION: PIS is a relatively common complication of EVAR used to treat AAAs and it is associated with features of a systemic inflammatory response and prolongation of hospitalization. Further studies are necessary towards understanding the underlying pathophysiology and evaluating effective preventive strategies. Interact Cardiovasc Thorac Surg |
| Databáze: | OpenAIRE |
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