Improving the catalytic efficiency of Pseudomonas aeruginosa lipoxygenase by semi-rational design

Autor: Cuiping, Pang, Song, Liu, Guoqiang, Zhang, Jingwen, Zhou, Guocheng, Du, Jianghua, Li
Rok vydání: 2023
Předmět:
Zdroj: Enzyme and Microbial Technology. 162:110120
ISSN: 0141-0229
DOI: 10.1016/j.enzmictec.2022.110120
Popis: Lipoxygenase (LOX) catalyzes the peroxidation of unsaturated fatty acids to produce hydroperoxides, which had been widely used in food, medicine and chemical industries due to its decoloration of food and conversion of renewable oils. Thus, higher catalytic activity and stability is desired for low-cost and expanded industrial applications of LOX. To improve the catalytic activity of LOX, a mutant library of Pseudomonas aeruginosa lipoxygenase (PaLOX) was firstly built via semi-rational design. The k
Databáze: OpenAIRE