The use of a perimeatal-based penile skin flap to cover the repair of a tubularized incised plate urethroplasty: from experimental surgery to clinical practice
| Autor: | Maria Agelidou, Christos Kalaitzis, Stavros Touloupidis, Stefanos Gardikis, George Vaos, Katerina Kambouri, Stilianos Giannakopoulos, Alexandra Giatromanolaki |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Tubularized incised plate urethroplasty medicine.medical_specialty Urologic Surgical Procedures Male Urology Fistula Urethroplasty medicine.medical_treatment Penile skin Surgical Flaps Urethra medicine Animals Experimental surgery Hypospadias business.industry Suture Techniques Skin Transplantation Plastic Surgery Procedures medicine.disease Meatal stenosis Surgery Clinical Practice Disease Models Animal Treatment Outcome Pediatrics Perinatology and Child Health Rabbits business Penis |
| Zdroj: | Journal of pediatric urology. 10(3) |
| ISSN: | 1873-4898 |
| Popis: | Objective To prospectively evaluate the efficacy and safety of a perimeatal-based penile skin flap for neourethral coverage after repair of distal hypospadias with tubularized incised plate urethroplasty (TIPU). Methods In 12 New Zealand white rabbits a ventral urethral defect was created and reconstruction was accomplished with continuous suture. An epithelialized defect-based flap was harvested from the penile skin to cover the repaired defect. The animals were euthanized on the 28th postoperative day and their penises were processed for microscopic examination. In 32 children with distal hypospadias a TIPU was performed. A penile skin flap was created immediately below the distal end of the neourethra and used to cover the urethroplasty. Results Histological examinations revealed complete restoration of continuity of the stratified squamous epithelium without evidence of inflammation or fistula formation with full consistency with the underlying papillary reticular and corium. There were no cases of fistula formation. One patient developed meatal stenosis. All patients had a satisfactory cosmetic appearance and excellent functional results. Conclusion The formation of a perimeatal-based skin flap is a simple and safe method of providing additional cover for the constructed neourethra after TIPU, minimizing the fistula rate. |
| Databáze: | OpenAIRE |
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