Glutamyl-transfer RNA: a precursor of heme and chlorophyll biosynthesis
| Autor: | Elizabeth Verkamp, Dieter Jahn, Dieter So¨ll |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Chlorophyll
Stereochemistry Molecular Sequence Data Heme Biology Biochemistry Cofactor Amino Acyl-tRNA Synthetases chemistry.chemical_compound Biosynthesis Glutamyl-tRNA reductase Sequence Homology Nucleic Acid Animals Amino Acid Sequence Isomerases Intramolecular Transferases Molecular Biology Bacteria RNA Aminolevulinic Acid Aldehyde Oxidoreductases Porphyrin RNA Transfer Glu chemistry Transfer RNA biology.protein |
| Zdroj: | Trends in Biochemical Sciences. 17:215-218 |
| ISSN: | 0968-0004 |
| DOI: | 10.1016/0968-0004(92)90380-r |
| Popis: | In green plants, archaebacteria and many eubacteria, the porphyrin ring that is common to both chlorophyll and heme is synthesized from 5-aminolevulinic acid (ALA) via an interesting pathway. This two-step process involves the unusual enzymes glutamyl-tRNA reductase and glutamate-1-semialdehyde 2,1-aminomutase. Interest in this pathway has increased since it was discovered that a tRNA cofactor was required for the formation of ALA. This tRNA(Glu) is common to the biosyntheses of both porphyrins and proteins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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