Effect of Denture Base Fabrication Technique on Candida albicans Adhesion In Vitro

Autor: Eran Dolev, Helena Zelikman, Avi Meirowitz, Eti Shlomo, Arkadi Rahmanov, Nir Sterer
Rok vydání: 2021
Předmět:
medicine.medical_treatment
biofilm adhesion
Dentistry
02 engineering and technology
lcsh:Technology
Article
Contact angle
dentures
03 medical and health sciences
0302 clinical medicine
medicine
General Materials Science
lcsh:Microscopy
Candida albicans
Bradford protein assay
Acrylic resin
Stomatitis
Curing (chemistry)
Candida
lcsh:QC120-168.85
lcsh:QH201-278.5
biology
lcsh:T
business.industry
Chemistry
technology
industry
and agriculture
030206 dentistry
Adhesion
021001 nanoscience & nanotechnology
biology.organism_classification
medicine.disease
lcsh:TA1-2040
visual_art
visual_art.visual_art_medium
lcsh:Descriptive and experimental mechanics
lcsh:Electrical engineering. Electronics. Nuclear engineering
Dentures
lcsh:Engineering (General). Civil engineering (General)
0210 nano-technology
business
lcsh:TK1-9971
Zdroj: Materials
Volume 14
Issue 1
Materials, Vol 14, Iss 221, p 221 (2021)
ISSN: 1996-1944
Popis: Denture stomatitis is a common manifestation of oral candidiasis affecting some 65% of denture wearers. This condition is initiated by the adherence of Candida albicans to denture base acrylic resin. The present study aimed to test the in vitro effect of traditional and novel fabrication methods on Candida albicans adhesion to denture base samples. Denture based acrylic discs were fabricated using: (i) computerized milling, (ii) 3D printing, (iii) heat curing, and (iv) cold curing. Discs were tested for surface roughness (Ra), hydrophobicity (contact angle), mucin adsorption (Bradford assay), and Candida albicans adhesion. 3D printing significantly increased microbial cell adhesion as compared with heat curing, and computerized milling significantly decreased it. These results were associated with mucin adsorption levels rather than surface roughness. Results suggest that 3D printing may increase the risk for developing denture stomatitis, whereas computerized milling may decrease it as compared with traditional heat curing denture base fabrication.
Databáze: OpenAIRE
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