Prevalence of small intestinal bacterial overgrowth in Chinese patients with Parkinson’s disease
| Autor: | Jian-Long Zhang, Qing Li, Li Liu, Zhi-Xiu Song, He-Hua Li, Zhi-Hua Wang, Xiao-Lu Niu |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease Neurology Logistic regression Gastroenterology Statistics Nonparametric Body Mass Index 03 medical and health sciences 0302 clinical medicine Blind loop syndrome Asian People Internal medicine Intestine Small Small intestinal bacterial overgrowth Prevalence medicine Humans Biological Psychiatry Aged Breath test medicine.diagnostic_test business.industry Case-control study Parkinson Disease Middle Aged medicine.disease Gastrointestinal Microbiome Surgery Psychiatry and Mental health Breath Tests Case-Control Studies Female 030211 gastroenterology & hepatology Neurology (clinical) Blind Loop Syndrome business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neural Transmission. 123:1381-1386 |
| ISSN: | 1435-1463 0300-9564 |
| DOI: | 10.1007/s00702-016-1612-8 |
| Popis: | Parkinson's disease (PD) is associated with gastrointestinal motility abnormalities that could favor the occurrence of small intestinal bacterial overgrowth (SIBO). The aim of the study was to assess the prevalence of SIBO in Chinese patients with PD and the potential impact of SIBO on gastrointestinal symptoms and motor function. 182 consecutive Chinese patients with PD patients and 200 sex, age, and BMI-matched subjects without PD were included. All participants underwent the glucose breath test to assess SIBO. We examined the associations between factors and SIBO with logistic regression using SPSS. Fifty-five of the 182 PD patients were SIBO positive (30.2 %; 95 % CI 23.5-36.9 %) compared with 19 of 200 in the control group (9.5 %; 95 % CI 5.4-13.6 %); the difference was statistically significant (P |
| Databáze: | OpenAIRE |
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