Should the definition of preeclampsia include a rise in diastolic blood pressure of/=15 mm Hg to a level90 mm Hg in association with proteinuria?
| Autor: | Richard J. Levine, M. G. Ewell, John C. Hauth, C. D. Morris, L. B. Curet, G. Choudhary, Bahaeddine M Sibai, P. M. Catalano |
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| Rok vydání: | 2000 |
| Předmět: |
Gestational hypertension
medicine.medical_specialty Diastole Blood Pressure Prehypertension Preeclampsia Body Mass Index Pre-Eclampsia Pregnancy Reference Values Internal medicine Terminology as Topic medicine Birth Weight Humans Proteinuria business.industry Cesarean Section Body Weight Infant Newborn Pregnancy Outcome Obstetrics and Gynecology medicine.disease Endocrinology Blood pressure Cardiology Gestation Female medicine.symptom business |
| Zdroj: | American journal of obstetrics and gynecology. 183(4) |
| ISSN: | 0002-9378 |
| Popis: | Objective: This study was undertaken to compare baseline characteristics and pregnancy outcomes between normotensive women who did and those who did not have a rise in diastolic blood pressure of ≥15 mm Hg in association with proteinuria. Study Design: We studied 4302 healthy nulliparous women from the Calcium for Preeclampsia Prevention trial who were delivered at ≥20 weeks’ gestation. We selected as the study group normotensive women who developed proteinuria within 7 days of a rise in diastolic blood pressure of ≥15 mm Hg with respect to baseline on 2 occasions 4 to 168 hours apart. Baseline blood pressure was the mean of measurements at 2 clinic visits before 22 weeks’ gestation. Other normotensive women used for comparison were those who did not develop gestational hypertension or a rise in diastolic blood pressure of ≥15 mm Hg in association with proteinuria. Results: Except for greater weight (P < .001), body mass index (P < .001), and systolic blood pressure (P = .05) the baseline characteristics of the 82 women with a rise in diastolic blood pressure of ≥15 mm Hg in association with proteinuria did not differ significantly from those of the other normotensive women. Although they had a greater rate of weight gain (P < .005), larger babies (P = .06), and a 2-fold increase in abdominal delivery (P < .001), there was little other evidence of adverse pregnancy outcomes among these women. Conclusion: During normotensive pregnancy a rise in diastolic blood pressure of ≥15 mm Hg in association with proteinuria appears to be benign and is not a useful clinical construct. (Am J Obstet Gynecol 2000;183:787-92.) |
| Databáze: | OpenAIRE |
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