Endoscope presence during endoluminal functional lumen imaging probe (FLIP) influences FLIP metrics in the evaluation of esophageal dysmotility
| Autor: | Amanda V. Bianca, Daniel Pohl, Chandra Prakash Gyawali, Fritz Murray, Valeria Schindler, Daniel Runggaldier, Larissa Schnurre |
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| Přispěvatelé: | University of Zurich, Pohl, Daniel |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Endoscope Physiology Achalasia 610 Medicine & health 10045 Clinic for Otorhinolaryngology Distension Balloon Endoscopy Gastrointestinal Young Adult 03 medical and health sciences 0302 clinical medicine Humans Medicine Esophageal Motility Disorders 2715 Gastroenterology Aged Aged 80 and over medicine.diagnostic_test Endocrine and Autonomic Systems business.industry Gastroenterology 1314 Physiology Middle Aged medicine.disease Endoscopy Endoscopes Gastrointestinal 2807 Endocrine and Autonomic Systems 10219 Clinic for Gastroenterology and Hepatology Esophageal motility disorder Flip 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Esophagogastric Junction business Nuclear medicine Lumen (unit) |
| Zdroj: | Neurogastroenterology & Motility. 32 |
| ISSN: | 1365-2982 1350-1925 |
| DOI: | 10.1111/nmo.13823 |
| Popis: | BACKGROUND: The functional lumen imaging probe (FLIP) system is an FDA-approved tool for dynamic evaluation of the esophagogastric junction (EGJ). Even though commercially available since 2009, FLIP utilization remains low, partly due to lack of consensus in methodology and interpretation. Therefore, we aimed to analyze the influence of concurrent endoscopy on FLIP measurements. METHODS: In this single-center study, we reviewed data from 93 patients undergoing FLIP for symptomatic esophageal motility disorders between 2016 and 2018. During sedated endoscopy, we measured luminal values (distensibility, cross-sectional area (CSA), and balloon pressure) at the EGJ and distal esophagus using 30, 40, and 50 mL distension volumes, with and without concurrent endoscope presence. All recorded values were compared at the various distension volumes between the two measurements using a Wilcoxon rank sum test. KEY RESULTS: There was a significant difference in distensibility and CSA with index distension volume (40 mL) at the EGJ comparing the two measurements: Lower median distensibility was 2.1 mm$^{2}$ mm Hg$^{-1}$ in the group with concurrent inserted endoscope, respectively, 3.4 mm$^{2}$ mm Hg$^{-1}$ without endoscope (P |
| Databáze: | OpenAIRE |
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