Magnetic Resonance Female Breast Imaging (MRFBI) - Evaluation of the Changes in Signal Intensity over Time Pre- and Post-administration of 0.2 mmol/kg Gd-DTPA
| Autor: | R. Felix, Kissner T, J. U. Blohmer, Oellinger H, Siewert C, Hadijuana J, Kohlschein P, Schedel H |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Gadolinium DTPA medicine.medical_specialty Breast imaging Contrast Media Breast Neoplasms Malignancy Sensitivity and Specificity Diagnosis Differential Lesion Breast Diseases Mole medicine Carcinoma Humans Breast MRI Breast Aged Neoplasm Staging medicine.diagnostic_test business.industry Carcinoma Ductal Breast Obstetrics and Gynecology Magnetic resonance imaging Middle Aged Image Enhancement medicine.disease Magnetic Resonance Imaging Carcinoma Intraductal Noninfiltrating Female Radiology Signal intensity medicine.symptom Nuclear medicine business |
| Zdroj: | Zentralblatt für Gynäkologie. 124:104-110 |
| ISSN: | 1438-9762 0044-4197 |
| DOI: | 10.1055/s-2002-24233 |
| Popis: | PURPOSE We are looking for a threshold value to discriminate between benign and malign breast lesions in MRI of female breast after administration of 0.2 mmol Gadolinum-DTPA/kg bw. MATERIALS AND METHODS Double coil breast MRI (1.5 Tesla) were performed in 65 patients with an suspicious lesion for malignancy in an anteriorly examination. 57 patients could be evaluated in our study design. Histopathological 35 patients had an invasive carcinoma, 3 patients had an in-situ-carcinoma and in 27 patients benign changes were found. RESULTS For different carcinoma diameters we found a different increase of signal intensity (SI): small carcinoma (< 10 mm) had an maximum increase of SI of 102 %, medium sized (10 to 20 mm) 222 % and carcinomas over 20 mm showed an increase of 271 %. We did not find a significant difference between SI in benign and malign lesions. The sensitivity was 94.6 % the specificity 65 %. CONCLUSION A threshold value to distinguish between malign and benign in MRI could not be defined. With the double normal Gd-DTPA dose we do not have better specificity and sensitivity than for normal dose (0.1 mmol/kg bw) is described. |
| Databáze: | OpenAIRE |
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