Cyto-histological correlations in primary, recurrent and metastatic rhabdomyosarcoma: The institut Curie's experience
Autor: | Hervé Brisse, J. M. Caillaud, Xavier Sastre-Garau, Paul Fréneaux, Philippe Vielh, Stamatios Theocharis, Jérôme Couturier, Réal Lagacé, Jerzy Klijanienko, Daniel Orbach |
---|---|
Rok vydání: | 2007 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Histology Adolescent Biopsy Fine-Needle Round cell sarcoma Pathology and Forensic Medicine Diagnosis Differential Cytologic material Cytology Rhabdomyosarcoma Atypia Humans Medicine Carcinoma Small Cell Child Retrospective Studies business.industry Infant Newborn Infant Sarcoma General Medicine medicine.disease Child Preschool Female Neoplasm Recurrence Local business |
Zdroj: | Diagnostic Cytopathology. 35:482-487 |
ISSN: | 1097-0339 8755-1039 |
Popis: | To determine diagnostic cytomorphologic features of rhabdomyosarcoma (RMS) on fine-needle aspiration (FNA) material, the cytologic material and corresponding histologic slides of 180 tumors obtained from 109 patients were reviewed. Fifty eight (32.2%) tumors were primary, 34 (18.9%) recurrent, and 88 (48.9%) metastatic. A review of original cytology reports revealed that 176 of 180 (97.8%) tumors were either diagnosed accurately or as round cell sarcoma, while 3 (1.7%) were reported as suspicious. In one case (0.5%), the material was unsatisfactory. No false negative samples were seen. When FNA morphology was correlated with different histological subtypes, the alveolar subtype RMSs were more cellular than the nonalveolar ones (91.4% vs. 64.9%). Similarly, alveolar subtype RMSs compared with nonalveolar ones exhibited more rhabdomyoblastic cells (77.1% vs. 52.7%), alveolar structures (67.6% vs. 10.8%), giant, multinucleated cells (22.9% vs. 6.7%), mitotic figures (57.1% vs. 18.9%), and cyto-nuclear atypia (77.1% vs. 43.2%). Inversely, spindle-shaped cells were more frequently seen in nonalveolar versus alveolar RMSs (37.8% vs. 20.9%). Diagn. Cytopathol. 2007;35:482–487. © 2007 Wiley-Liss, Inc. |
Databáze: | OpenAIRE |
Externí odkaz: |