Preoperative diagnosis of breast diseases by dynamic MR mammography: Cut-off point establishment for signal intensity ratio

Autor: Toshihiko Kajima, Takayasu Nagata, Kuniyasu Shimokawa, Susumu Tachibana, Juji Tsuchiya, Takashi Uno, Hajime Kawagoe, Mutsuo Hoshino
Rok vydání: 1998
Předmět:
Zdroj: Breast Cancer. 5:155-164
ISSN: 1880-4233
1340-6868
Popis: We have demonstrated that the dynamic study for breast lesions by magnetic resonance Imaging (MRI) can differentiate benign from malignant lesions objectively. The cases were57 histopathologically appraised breast lesions, including 20 cases of breast cancer, 28 cases of mastopathy, 8 cases of fibroadenoma and 1 case of intraductal papillomatosis. We plotted time-signal intensity ratio curves and then determined 95% confidence intervals, plotting the signal intensity ratio for both breast cancer and mastopathy every 30 seconds during dynamic magnetic resonance mammography (MRM) after gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) administration, and further established cut-off points to differentiate between them. We then tried of estimate objectively the benign-malignant differentiation to breast lesions by confirming their signal intensity ratio to be more or less than the cut-off points. We advocate this procedure, and call it the “dynamic ratio method.”As a result, we found highly significant differences between breast cancer and mastopathy at 30 and 60 seconds after Gd-DTPA administration (P
Databáze: OpenAIRE