Severe imported malaria: Clinical presentation at the time of hospital admission and outcome in 42 cases diagnosed from 1996 to 2002
| Autor: | Sékéné Badiaga, Claude Martin, Jean Claude Manelli, Jean Delmont, Philippe Brouqui, Jean Pierre Carpentier, Fabien Duigou, P. Hovette |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Plasmodium falciparum World Health Organization law.invention Patient Admission law Surveys and Questionnaires medicine Animals Humans Aged Retrospective Studies Coma Travel Quinine business.industry Retrospective cohort study Emergency department Middle Aged Jaundice medicine.disease Health Surveys Intensive care unit Malaria Treatment Outcome Chemoprophylaxis Emergency Medicine Female Prostration France medicine.symptom business |
| Zdroj: | The Journal of Emergency Medicine. 29:375-382 |
| ISSN: | 0736-4679 |
| DOI: | 10.1016/j.jemermed.2005.03.009 |
| Popis: | The objectives of this retrospective study were to describe initial clinical profiles and subsequent outcome of adult patients in France who were diagnosed with severe imported malaria, as defined by the World Health Organization (WHO). Forty-two patients diagnosed from 1996 to 2002 were included (median age: 30 years, men: 78%, non-immune persons: 74%, return from Africa: 100%, inappropriate antimalarial chemoprophylaxis: 95%). At the time of hospital admission, jaundice (62%), hyperparasitemia (56%), and prostration (52%) were the most frequent findings, followed by acute renal failure (31%). Other findings, as described by the WHO criteria, were less common. Twenty-three patients presented only with jaundice, hyperparasitemia, or prostration in isolation, or in combination. Of these 23, five non-immune persons subsequently developed coma, shock, acute respiratory distress syndrome or acute renal failure; this led to death in 2 of these cases. This suggests that non-immune persons with imported malaria who present with jaundice, hyperparasitemia, or prostration should be admitted to the intensive care unit for close monitoring. |
| Databáze: | OpenAIRE |
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