Dental implants in individuals living with HIV-1: Results from a prospective study in patients undergoing highly active antiretroviral therapy
| Autor: | Fábio Vidal, Rafael Vidal Peres, Rodrigo Carvalho de Souza, Lucio Souza Gonçalves, Cristiane Gonçalves, Priscila Pavan |
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| Rok vydání: | 2021 |
| Předmět: |
Dental Implants
medicine.medical_specialty Peri-implantitis business.industry medicine.medical_treatment medicine.disease Prosthesis Peri-Implantitis Supportive psychotherapy Internal medicine Diabetes mellitus Antiretroviral Therapy Highly Active Mucositis HIV-1 Medicine Humans Implant Prospective Studies business Prospective cohort study Dental implant General Dentistry |
| Zdroj: | Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryREFERENCES. 42(2) |
| ISSN: | 1754-4505 |
| Popis: | OBJECTIVE To assess survival and success rates of dental implants and the occurrence of peri-implant diseases (mucositis/peri-implantitis) in HIV-1-infected individuals. MATERIAL AND METHODS In this prospective study, 13 HIV-1-infected individuals undergoing highly active antiretroviral therapy (with undetectable plasma HIV RNA levels, and CD4+ T cells > 350/mm3 ) were followed after implant placement, as well as 13 non-HIV-1-infected matched controls. Patients enrolled in this study were followed up to 120 months (mean = 40.6 months; standard deviation = 22.2; range 18 -120 months). Twenty-five implants were placed in pristine healed sites for each group and bone augmentation procedures, when needed, were done only for contour augmentation. Patients were enrolled in a strict periodontal/peri-implant supportive therapy protocol with three recalls per year. The two groups were compared regarding subject-level characteristics (age, gender, smoking, diabetes) and implant-level characteristics (marginal bone level, peri-implant health status). RESULTS All the implants healed uneventfully and reached 100% survival rates (after at least 18 months) in both groups. There were no significant differences between groups for peri-implant diseases (mucositis/peri-implantitis) and for all subject-level co-variables (p > .05). Only the variables dental implant prosthesis type (DIPT) (p = .021, d = .86) and follow up (p = .011, d = .77) showed statistically significant differences between groups. CONCLUSION The findings suggest that well-controlled HIV-1-infected individuals are eligible to undergo implant therapy, achieving survival and success rates comparable to non-HIV-1-infected controls. |
| Databáze: | OpenAIRE |
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