Fractal analysis: a new biomarker for determining clot characteristics in critically ill patients

Autor:	Phillip A. Evans, D Gill, Dafydd Thomas, Matthew Lawrence, Phylip Rhodri Williams, Sophia N. Stanford, Gareth Davies, Keith Morris
Rok vydání:	2012
Předmět:	biology Critically ill business.industry Critical Care and Intensive Care Medicine Bioinformatics Clot formation Pathogenicity Fractal analysis Fibrin Biomarker (cell) Poster Presentation Critical illness biology.protein Medicine business circulatory and respiratory physiology
Zdroj:	Critical Care
Popis:	Recent research [1] has highlighted a novel new biomarker of haemostasis: the fractal dimension (Df). This new biomarker relates the kinetics of clot formation to clot outcome in whole blood and allows us to quantify the complexity of the fibrin network microstructure which is believed to be the template for development of the mature clot. It is well established that abnormalities in haemostasis contribute to the pathogenicity of critical illness [2]. This prospective study aims to assess the effect of critical illness on clot structure and monitor the sensitivity of Df to therapeutic intervention.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c37d262443096db8feec2a5566af41 https://cronfa.swan.ac.uk/Record/cronfa20027 Zobrazit plný text záznamu