Catheter and Laryngeal Mask Endotracheal Surfactant Therapy: the CALMEST approach as a novel MIST technique

Autor: Armando Cuttano, Antonio Boldrini, Massimiliano Ciantelli, Francesca Moscuzza, Rosa T. Scaramuzzo, Davide Panizza, Ilaria Vannozzi, Emilio Sigali
Rok vydání: 2016
Předmět:
Zdroj: The Journal of Maternal-Fetal & Neonatal Medicine. 30:2375-2377
ISSN: 1476-4954
1476-7058
DOI: 10.1080/14767058.2016.1248938
Popis: Purpose: Neonatal respiratory distress syndrome (RDS) is a major cause of mortality and morbidity among preterm infants. Although the INSURE (INtubation, SURfactant administration, Estubation) technique for surfactant replacement therapy is so far the gold standard method, over the last years new approaches have been studied, i.e. less invasive surfactant administration (LISA) or minimally invasive surfactant therapy (MIST). Here we propose an originally modified MIST, called CALMEST (Catheter And Laryngeal Mask Endotracheal Surfactant Therapy), using a particular laryngeal mask as a guide for a thin catheter to deliver surfactant directly in the trachea.Materials and methods: We performed a preliminary study on a mannequin and a subsequent in vivo pilot trial.Results and conclusions: This novel procedure is quick, effective and well tolerated and might represent an improvement in reducing neonatal stress. Ultimately, CALMEST offers an alternative approach that could be extremely useful for medica...
Databáze: OpenAIRE