Catheter and Laryngeal Mask Endotracheal Surfactant Therapy: the CALMEST approach as a novel MIST technique
Autor: | Armando Cuttano, Antonio Boldrini, Massimiliano Ciantelli, Francesca Moscuzza, Rosa T. Scaramuzzo, Davide Panizza, Ilaria Vannozzi, Emilio Sigali |
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Rok vydání: | 2016 |
Předmět: |
Male
Neonatal respiratory distress syndrome medicine.medical_specialty medicine.medical_treatment Less invasive Pilot Projects Surfactant therapy Laryngeal Masks 03 medical and health sciences 0302 clinical medicine Pulmonary surfactant 030225 pediatrics medicine Humans Intubation 030212 general & internal medicine Respiratory Distress Syndrome Newborn Respiratory distress business.industry Infant Newborn Mist Obstetrics and Gynecology Pulmonary Surfactants medicine.disease Surgery Catheter Anesthesia Pediatrics Perinatology and Child Health Female business |
Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 30:2375-2377 |
ISSN: | 1476-4954 1476-7058 |
DOI: | 10.1080/14767058.2016.1248938 |
Popis: | Purpose: Neonatal respiratory distress syndrome (RDS) is a major cause of mortality and morbidity among preterm infants. Although the INSURE (INtubation, SURfactant administration, Estubation) technique for surfactant replacement therapy is so far the gold standard method, over the last years new approaches have been studied, i.e. less invasive surfactant administration (LISA) or minimally invasive surfactant therapy (MIST). Here we propose an originally modified MIST, called CALMEST (Catheter And Laryngeal Mask Endotracheal Surfactant Therapy), using a particular laryngeal mask as a guide for a thin catheter to deliver surfactant directly in the trachea.Materials and methods: We performed a preliminary study on a mannequin and a subsequent in vivo pilot trial.Results and conclusions: This novel procedure is quick, effective and well tolerated and might represent an improvement in reducing neonatal stress. Ultimately, CALMEST offers an alternative approach that could be extremely useful for medica... |
Databáze: | OpenAIRE |
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