The clinical evaluation of a new clobetasol propionate preparation in the treatment of otitis externa
| Autor: | R. F. E. Gray, R. P. E. Barton, J. L. W. Wright |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male medicine.medical_specialty Nystatin Adolescent Hydrocortisone Unilateral disease Betamethasone Random Allocation Double-Blind Method medicine Humans Polymyxins Child Aged Clinical Trials as Topic Clobetasol business.industry Neomycin General Medicine Middle Aged Tetracycline Otitis Externa Dermatology Clinical trial Drug Combinations Otitis Otorhinolaryngology Female Clobetasol propionate medicine.symptom business Clinical evaluation medicine.drug |
| Zdroj: | The Journal of laryngology and otology. 93(7) |
| ISSN: | 0022-2151 |
| Popis: | A new preparation containing clobetasol propionate, tetracycline and nystatin was compared with Otosporin in the the treatment of otitis externa. Thirty-two patients with bilateral disease and seventeen with unilateral disease completed the trial. Signs and symptoms were assessed by the clinician initially and at varying times after treatment. Both preparations were effective in relieving the symptoms with the majority of patients noticing improvement within seven days. Clobetasol propionate ear drops were significantly better than Otosporin when assessed on the patient's last visit to the hospital (p less than 0.05). There were less relapses in the clobetasol propionate group than in the Otosporin group. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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