Balancing Thrombotic Events and Bleeding in Primary PCI

Autor: Shamir R. Mehta
Rok vydání: 2013
Předmět:
Zdroj: New England Journal of Medicine. 369:2263-2265
ISSN: 1533-4406
0028-4793
Popis: Primary percutaneous coronary intervention (PCI) has become the preferred method of reperfusion for patients with ST-segment elevation myocardial infarction (STEMI) when the procedure can be performed promptly by experts. Anticoagulation is important in patients undergoing primary PCI because it prevents acute thrombus formation at the site of arterial injury and on PCI-related hardware.1 Major bleeding that is associated with antithrombotic therapy is independently associated with subsequent death and recurrent ischemic events, and this relationship may be causal.2,3 One approach to reduce bleeding is to use antithrombotic therapies with better safety profiles. In the Harmonizing Outcomes with Revascularization and Stents . . .
Databáze: OpenAIRE