Perinatal Infections With Ureaplasma

Autor: Wendy W. J. Unger, Jop Jans, Kim Stol, Lisa Ott de Bruin, Annemarie M. C. van Rossum
Rok vydání: 2021
Předmět:
Zdroj: Pediatric Infectious Disease Journal. 40:S26-S30
ISSN: 0891-3668
DOI: 10.1097/inf.0000000000002859
Popis: Ureaplasma species are increasingly recognized as relevant pathogens in prenatal, perinatal and postnatal morbidity. They are commonly found as commensals on the mucous membranes of the lower urogenital tract of pregnant women, but when ascending, they can cause bacterial vaginosis, chorioamnionitis, premature birth and postnatal morbidities such as bronchopulmonary dysplasia, and early-onset neonatal sepsis and meningitis. The detection of Ureaplasma species is challenging and is not covered by routine diagnostics, and current empiric antibiotic treatment in neonates suspected of infection is not directed against Ureaplasma species. The aim of this review is to discuss the pathophysiology of Ureaplasma infections, the clinical consequences and the current difficulties in diagnosis and treatment by providing an overview of the current literature.
Databáze: OpenAIRE