Inner ear enhancement on gadolinium-enhanced 3D FLAIR images in a patient with Vogt–Koyanagi–Harada disease
Autor: | Kosuke Hida, Koichi Takano, Kengo Yoshimitsu, Jiro Fukae, Koichi Hokao |
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Rok vydání: | 2017 |
Předmět: |
Vogt–Koyanagi–Harada disease
Pathology medicine.medical_specialty business.industry Leptomeninges Retinal detachment Case Report General Medicine Fluid-attenuated inversion recovery Fundus (eye) medicine.disease eye diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure otorhinolaryngologic diseases medicine sense organs Choroid medicine.symptom 030223 otorhinolaryngology business 030217 neurology & neurosurgery Tinnitus Uveitis |
Zdroj: | BJR Case Reports |
ISSN: | 2055-7159 |
DOI: | 10.1259/bjrcr.20160090 |
Popis: | Vogt–Koyanagi–Harada (VKH) disease is an autoimmune disorder that occurs in the melanocytes present in the uvea, leptomeninges, skin and inner ear. Clinically, this disease is characterized by bilateral uveitis and retinal detachment and is associated with meningismus and hearing loss. Gadolinium (Gd)-enhanced MRI may aid in demonstrating bilateral choroidal thickening and central nervous system involvement. We present a case of VKH where Gd-enhanced three-dimensional (3D) fluid attenuation inversion recovery (FLAIR) imaging showed abnormal bilateral enhancement in the inner ears. A 36-year-old female was referred to our institution with symptoms of visual disturbance, headache and tinnitus, and was diagnosed with VKH based on fundus examination and clinical presentations. MRI findings revealed bilateral enhancement in the choroid, leptomeninges, and inner ears. In particular, Gd-enhanced 3D FLAIR showed more conspicuous enhancement of the leptomeninges and inner ear compared with Gd-enhanced 3D T1 weighted image. Therefore, Gd-enhanced 3D FLAIR imaging can be used when leptomeningeal or inner ear pathology is clinically suspected. |
Databáze: | OpenAIRE |
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