Effect of intracerebral injection of chlorpromazine and diazepam on acid phosphatase activity in the mouse brain
Autor: | R.K. Tanwar, J.S. Sethi |
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Rok vydání: | 1990 |
Předmět: |
medicine.medical_specialty
Histology Chlorpromazine Central nervous system Cell Acid Phosphatase Hippocampal formation Injections Mice Internal medicine medicine Animals Tissue Distribution Neocortex Diazepam biology Chemistry Acid phosphatase food and beverages Brain medicine.anatomical_structure Endocrinology Anesthesia biology.protein Anatomy Pyramidal cell medicine.drug |
Zdroj: | Acta anatomica. 138(2) |
ISSN: | 0001-5180 |
Popis: | Chlorpromazine (CPZ) administration resulted in an increase in acid phosphatase (AcP) activity in the lamina VI of the neocortex pyramidal cell layer granular cell layer and hilus of the hippocampal formation. Diazepam (DZ) administration also induced an increase in AcP activity in the lamina VI of the neocortex and in the pyramidal cell layer of the hippocampal formation. The large-sized pyramidal cells of the hippocampal formation indicated a more prominent and continuous reaction in the cell processes during the administration of CPZ and DZ. The possible role of CPZ and DZ has been discussed in relation to the AcP activity in the regions studied. |
Databáze: | OpenAIRE |
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