Normobaric oxygen paradox and erythropoietin production in critically ill patients: a prospective observational study

Autor: Elisa Damiani, Abele Donati, Samuele Zuccari, R Castagnani, Paolo Pelaia, Nicoletta Mininno
Jazyk: angličtina
Předmět:
Zdroj: Europe PubMed Central
Critical Care
ISSN: 1364-8535
DOI: 10.1186/cc14400
Popis: The normobaric oxygen paradox (NOP) postulates that a period of normobaric hyperoxia followed by a rapid return to normoxia will create a condition of relative hypoxia, which acts in turn as a stimulus for erythropoietin (EPO) production [1]. Variations in GSH and oxygen free radical (ROS) levels may be involved in this process. We tested the NOP in critically ill patients.
Databáze: OpenAIRE