Normobaric oxygen paradox and erythropoietin production in critically ill patients: a prospective observational study
Autor: | Elisa Damiani, Abele Donati, Samuele Zuccari, R Castagnani, Paolo Pelaia, Nicoletta Mininno |
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Jazyk: | angličtina |
Předmět: | |
Zdroj: | Europe PubMed Central Critical Care |
ISSN: | 1364-8535 |
DOI: | 10.1186/cc14400 |
Popis: | The normobaric oxygen paradox (NOP) postulates that a period of normobaric hyperoxia followed by a rapid return to normoxia will create a condition of relative hypoxia, which acts in turn as a stimulus for erythropoietin (EPO) production [1]. Variations in GSH and oxygen free radical (ROS) levels may be involved in this process. We tested the NOP in critically ill patients. |
Databáze: | OpenAIRE |
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