Nutritional management of patients with acute pancreatitis: a Dutch observational multicentre study

Autor:	B W M, Spanier, E M H, Mathus-Vliegen, H A R E, Tuynman, R W M, Van der Hulst, M G W, Dijkgraaf, M J, Bruno, C Y, Ponsioen
Přispěvatelé:	Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Gastroenterology and Hepatology, Amsterdam Public Health, Epidemiology and Data Science, Other departments
Jazyk:	angličtina
Rok vydání:	2008
Předmět:	Male medicine.medical_specialty Parenteral Nutrition Time Factors Enteral administration Cohort Studies Enteral Nutrition Internal medicine medicine Humans Pharmacology (medical) Prospective Studies Prospective cohort study Netherlands Starvation Hepatology business.industry Gastroenterology Length of Stay medicine.disease Surgery Regimen Parenteral nutrition Treatment Outcome Pancreatitis Acute Disease Acute pancreatitis Female medicine.symptom business Cohort study
Zdroj:	Alimentary pharmacology & therapeutics, 28(9), 1159-1165. Wiley-Blackwell
ISSN:	0269-2813
DOI:	10.1111/j.1365-2036.2008.03814.x
Popis:	Summary Background Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. Aim To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study). Methods Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed. Results In mild AP, a majority of cases (80.7%, 117/145) were managed with an NPO regimen only. Twenty-seven patients (18.6%) with mild AP additionally received TF; one received TPN. Of those with severe AP, more than half of the patients (56.2%, nine of 16) were treated with TF besides an NPO regimen; four received TPN. TF was delivered preferably via the jejunal route. The median period of total starvation was 2 days for both mild and severe AP. Only 5.5% (nine of 164) of patients had a prolonged starvation time of more than 5 days. Conclusions The total time of starvation was limited in a majority of patients admitted for AP. According to international guidelines, additional nutritional interventions were quickly undertaken with enteral feeding via the jejunum as the preferred route.
Databáze:	OpenAIRE
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