Nanocarriers as a Tool for the Treatment of Colorectal Cancer
Autor: | Timo Schomann, Ana Luiza C. de S. L. Oliveira, Ellen Kapiteijn, Lioe-Fee de Geus-Oei, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz |
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Rok vydání: | 2021 |
Předmět: |
Oncology
medicine.medical_specialty Colorectal cancer Pharmaceutical Science Review 03 medical and health sciences Pharmacy and materia medica 0302 clinical medicine Internal medicine Medicine Effective treatment drug delivery system cancer 030304 developmental biology 0303 health sciences biological barriers business.industry Cancer medicine.disease nanomedicine 3. Good health RS1-441 The Hallmarks of Cancer 030220 oncology & carcinogenesis Drug delivery Life expectancy Nanomedicine nanoparticles Nanocarriers business |
Zdroj: | Pharmaceutics Pharmaceutics, Vol 13, Iss 1321, p 1321 (2021) Pharmaceutics, 13(8) |
ISSN: | 1999-4923 |
Popis: | Nanotechnology is a promising tool for the treatment of cancer. In the past decades, major steps have been made to bring nanotechnology into the clinic in the form of nanoparticle-based drug delivery systems. The great hope of drug delivery systems is to reduce the side effects of chemotherapeutics while simultaneously increasing the efficiency of the therapy. An increased treatment efficiency would greatly benefit the quality of life as well as the life expectancy of cancer patients. However, besides its many advantages, nanomedicines have to face several challenges and hurdles before they can be used for the effective treatment of tumors. Here, we give an overview of the hallmarks of cancer, especially colorectal cancer, and discuss biological barriers as well as how drug delivery systems can be utilized for the effective treatment of tumors and metastases. |
Databáze: | OpenAIRE |
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