QTL detection for milk production traits in goats using a longitudinal model
| Autor: | Fernando Daniel Holgado, Silvina A. Saldaño, Mario Andres Poli, Rodolfo Juan Carlos Cantet, Alicia E. Rabasa, D. L. Roldán |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Genotype Quantitative Trait Loci LACTATION CURVE Breeding Biology Quantitative trait locus Longitudinal model Food Animals GOATS Animals Lactation Longitudinal Studies Genetics QUANTITATIVE TRAIT LOCI Models Genetic Goats General Medicine Milk Proteins Milk production Lipids Dairying Milk Phenotype Regression Analysis Female Animal Science and Zoology purl.org/becyt/ford/4.3 [https] purl.org/becyt/ford/4 [https] Microsatellite Repeats |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| ISSN: | 1439-0388 0931-2668 |
| DOI: | 10.1111/j.1439-0388.2007.00714.x |
| Popis: | Summary Eight paternal half-sib families were used to identify chromosomal regions associated with variation in the lactation curves of dairy goats. DNA samples from 162 animals were amplified by PCR for 37 microsatellite markers, from Capra hircus autosomes CHI3, CHI6, CHI14 and CHI20. Milk samples were collected during 6 years, and there were 897 records for milk yield (MY) and 814 for fat (FP) and protein percentage (PP). The analysis was conducted in two stages. First, a random regression model with several fixed effects was fitted to describe the lactation function, using a scale (α) plus four shape parameters: β and γ, both associated with a decrease in the slope of the curve, and δ and φ that are related to the increase in slope. Predictions of α, β, γ, δ and φ were regressed using an interval mapping model, and F-tests were used to test for quantitative trait loci (QTL) effects. Significant (p < 0.05) QTLs were found for: (i) MY: CHI6 at 70-80 cM for all parameters; CHI14 at 14 cM for δ and φ; (ii) FP: CHI14, at 63 cM was associated with β; CHI20, at 72 cM, showed association with α; (iii) PP: chromosomal regions associated with β were found at 59 cM in CHI3 and at 55 cM in CHI20 with α and γ. Analyses using more families and more animals will be useful to confirm or to reject these findings. © 2008 Blackwell Verlag, Berlin. Fil: Roldán, D.L.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Genética; Argentina Fil: Rabasa, Alicia Elvira. Universidad Nacional de Tucumán. Facultad de Agronomía y Zootecnia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán; Argentina Fil: Saldaño, S.. Universidad Nacional de Tucumán. Facultad de Agronomía y Zootecnia; Argentina Fil: Holgado, F.. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Tucuman-santiago del Estero. Campo Experimental Regional Leales; Argentina Fil: Poli, M. A.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Genética; Argentina Fil: Cantet, Rodolfo Juan Carlos. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina |
| Databáze: | OpenAIRE |
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