The critical barrier to progress in dentine bonding with the etch-and-rinse technique

Autor: Yi Pin Qi, Alejandro Dib, Martha G Brackett, N. Li, César Rogério Pucci, Franklin R. Tay, Rhoda J. Sword, William W. Brackett, David H. Pashley, Li Na Niu
Rok vydání: 2011
Předmět:
Time Factors
Materials science
Adolescent
Adhesive bonding
Fibrillar Collagens
medicine.medical_treatment
Acrylic Resins
Organophosphonates
Dental bonding
Matrix Metalloproteinase Inhibitors
Composite Resins
Article
Dental Materials
Dental cavity preparation
Acid Etching
Dental
Microscopy
Electron
Transmission
Polymethacrylic Acids
stomatognathic system
Biomimetics
medicine
Dentin
Humans
Bisphenol A-Glycidyl Methacrylate
Phosphoric Acids
Composite material
Child
Dental Restoration
Permanent
General Dentistry
Minerals
Chlorhexidine
Dental Bonding
technology
industry
and agriculture
Saliva
Artificial
Water
Nanostructures
stomatognathic diseases
medicine.anatomical_structure
Solubility
Dentin-Bonding Agents
Tooth Remineralization
Polyvinyls
Adhesive
Etch and rinse
Dental Cavity Preparation
Dental restoration
Zdroj: Journal of Dentistry. 39:238-248
ISSN: 0300-5712
DOI: 10.1016/j.jdent.2010.12.009
Popis: The lack of durability in resin-dentine bonds led to the use of chlorhexidine as MMP-inhibitor to prevent the degradation of hybrid layers. Biomimetic remineralisation is a concept-proven approach in preventing the degradation of resin-dentine bonds. The purpose of this study is to examine the integrity of aged resin-dentine interfaces created with a nanofiller-containing etch-and-rinse adhesive after the application of these two approaches.The more established MMP-inhibition approach was examined using a parallel in vivo and in vitro ageing design to facilitate comparison with the biomimetic remineralisation approach using an in vitro ageing design. Specimens bonded without chlorhexidine exhibited extensive degradation of the hybrid layer after 12 months of in vivo ageing.Dissolution of nanofillers could be seen within a water-rich zone within the adhesive layer. Although specimens bonded with chlorhexidine exhibited intact hybrid layers, water-rich regions remained in those hybrid layers and degradation of nanofillers occurred within the adhesive layer. Specimens subjected to in vitro biomimetic remineralisation followed by in vitro ageing demonstrated intrafibrillar collagen remineralisation within hybrid layers and deposition of mineral nanocrystals in nanovoids within the adhesive.The impact was realized by understanding the lack of an inherent mechanism to remove water from resin-dentine interfaces as the critical barrier to progress in bonding with the etch-and-rinse technique. The experimental biomimetic remineralisation strategy offers a creative solution for incorporating a progressive hydration mechanism to achieve this goal, which warrants its translation into a clinically applicable technique.
Databáze: OpenAIRE
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