Trends in urinary tract infection hospitalization in older adults in Spain from 2000-2015

Autor: Miguel López-Miguel, Elena Polentinos-Castro, Ricardo Rodríguez-Barrientos, Laura Llamosas-Falcón, Ángel Gil de Miguel, Lucas Marina-Ono, Laura Diez-Izquierdo, Isabel del Cura-González, Jesús Redondo-Sánchez, Francisco Rodríguez-Cabrera
Přispěvatelé: Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Fundación de Investigación e Innovación Biosanitaria en Atención Primaria, Plan Nacional de I+D+i (España)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Joinpoint regression
Epidemiology
Comorbidity
Endocrinology
Cost of Illness
Cystitis
Medicine and Health Sciences
Statistical analysis
Aged
80 and over
Multidisciplinary
Pyelonephritis
Incidence
Bladder and Ureteric Disorders
Hospitals
Prostatitis
Hospitalization
Urinary Tract Infections
Medicine
Female
Research Article
medicine.medical_specialty
Endocrine Disorders
Urology
Urinary system
Science
Microbiology
Microbial Control
Internal medicine
medicine
Humans
In patient
Health planning
Aged
Retrospective Studies
Pharmacology
Genitourinary Infections
business.industry
Biology and Life Sciences
Retrospective cohort study
Length of Stay
medicine.disease
Health Care
Age Groups
Health Care Facilities
Spain
Antibiotic Resistance
People and Places
Population Groupings
Antimicrobial Resistance
business
Zdroj: PLoS ONE, Vol 16, Iss 9, p e0257546 (2021)
PLoS ONE
Repisalud
Instituto de Salud Carlos III (ISCIII)
ISSN: 1932-6203
Popis: Objective: To analyze trends in urinary tract infection hospitalization (cystitis, pyelonephritis, prostatitis and non-specified UTI) among patients over 65 years in Spain from 2000-2015. Methods: We conducted a retrospective observational study using the Spanish Hospitalization Minimum Data Set (CMBD), with codifications by the International Classification of Diseases (ICD-9). We collected data on sex, age, type of discharge, main diagnosis, comorbid diagnosis, length of stay, and global cost. All the hospitalizations were grouped by age into three categories: 65-74 years old, 75-84 years old, and 85 years old and above. In the descriptive statistical analysis, crude rates were defined as hospitalizations per 1,000 inhabitants aged ≥65. To identify trends over time, we performed a Joinpoint regression. Results: From 2000-2015, we found 387,010 hospitalizations coded as UTIs (54,427 pyelonephritis, 15,869 prostatitis, 2643 cystitis and 314,071 non-specified UTI). The crude rate of hospitalization for UTIs between 2000 and 2015 ranged from 2.09 in 2000 to 4.33 in 2015 Rates of hospitalization were higher in men than in women, except with pyelonephritis. By age group, higher rates were observed in patients aged 85 years or older, barring prostatitis-related hospitalizations. Joinpoint analyses showed an average annual percentage increase (AAPC) in incidence rates of 4.9% (95% CI 3.2;6.1) in UTI hospitalizations. We observed two joinpoints, in 2010 and 2013, that found trends of 5.5% between 2000 and 2010 (95% CI 4.7;6.4), 1.5% between 2010 and 2013 (95% CI -6.0;9.6) and 6.8% between 2013 and 2015 (95% CI -0.3;14.4). Conclusions: The urinary infection-related hospitalization rate in Spain doubled during the period 2000-2015. The highest hospitalization rates occurred in men, in the ≥85 years old age group, and in non-specified UTIs. There were increases in all types of urinary tract infection, with non-specified UTIs having the greatest growth. Understanding these changing trends can be useful for health planning. This study has been funded by Instituto de Salud Carlos III through the project “PI19/01700”, as part of the Plan Estatal de I+D+I 2017-2020 co-funded by European Regional Development Fund (ERDF) “A way of shaping Europe”. In addition, the principal investigator JRS received support to increase his research activities and to publish this manuscript from the 2020 funding program of the Fundación de Investigación e Innovación Biosanitaria en Atención Primaria (FIIBAP), Community of Madrid. Sí
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje