Hepatic fat quantification using the proton density fat fraction (PDFF): utility of free-drawn-PDFF with a large coverage area
| Autor: | Stephan Kannengiesser, Ji Soo Song, Kun Young Kim, Young Min Han |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male In vivo magnetic resonance spectroscopy Magnetic Resonance Spectroscopy Adolescent Fat quantification Fats medicine Humans Radiology Nuclear Medicine and imaging Child Aged Aged 80 and over medicine.diagnostic_test business.industry Ultrasound Proton density fat fraction Magnetic resonance imaging General Medicine Middle Aged Reference Standards medicine.disease Magnetic Resonance Imaging Mr imaging Lobe Fatty Liver medicine.anatomical_structure Liver Female Steatosis business Nuclear medicine |
| Zdroj: | La radiologia medica. 120:1083-1093 |
| ISSN: | 1826-6983 0033-8362 |
| DOI: | 10.1007/s11547-015-0545-x |
| Popis: | To evaluate the diagnostic performance of magnetic resonance imaging-estimated proton density fat fraction (MRI-PDFF) using a free-drawn region-of-interest (ROI) measurement of hepatic fat deposition compared to MR spectroscopy (MRS) as the reference standard. A total of 156 patients underwent 3T MR imaging with a multi-step adaptive fitting approach, multi-echo volume interpolated breath-hold examination (VIBE) acquisition and single-voxel high-speed T2-corrected multiple-echo 1H-MR spectroscopy (SVS). Seven ROI measurements were performed in each segment of the fat percentage maps (“segmental-PDFF”). Three ROIs were placed at the same level as the SVS (“VOI-PDFF”). Free-hand-drawn ROIs were placed at three different levels along the entire liver (“free-drawn-PDFF”) and separately along the right and left lobes (“free-drawn-PDFF-2”). A strong correlation was found between VOI-PDFF and SVS (r = 0.977). The right lobe had greater fat content than the left lobe (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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