Endovascular Versus Medical Therapy for Atherosclerotic Renovascular Disease
Autor: | David A Folt, Kaleigh L. Evans, Christopher J. Cooper, Mark Shipeng Yu, Emily L. Cooper, Steven T. Haller, Christopher A. Drummond, Pamela Brewster |
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Rok vydání: | 2014 |
Předmět: |
Male
medicine.medical_specialty Hypertension Renal medicine.medical_treatment Angiotensin-Converting Enzyme Inhibitors Disease Renal Artery Obstruction Renal artery stenosis Risk Assessment Severity of Illness Index Article law.invention Randomized controlled trial law Angioplasty Internal medicine Severity of illness medicine Humans Survival rate Antihypertensive Agents Aged Randomized Controlled Trials as Topic Angiology Evidence-Based Medicine business.industry Endovascular Procedures Middle Aged Atherosclerosis Prognosis medicine.disease Survival Rate Treatment Outcome Renal pathology Cardiology Female Stents Cardiology and Cardiovascular Medicine business Angioplasty Balloon |
Zdroj: | Current Atherosclerosis Reports. 16 |
ISSN: | 1534-6242 1523-3804 |
Popis: | The diagnosis of renal artery stenosis (RAS) has become increasingly common in part due to greater awareness of ischemic renal disease and increased use of diagnostic techniques. Over 90 % of RAS cases are caused by atherosclerotic renovascular disease (ARVD). Patients with ARVD are at high risk for fatal and nonfatal cardiovascular and renal events. The mortality rate in patients with ARVD is high, especially with other cardiovascular or renal comorbidities. Recent clinical studies have provided substantial evidence concerning medical therapy and endovascular interventional therapeutic approaches for ARVD. Despite previous randomized clinical trials, the optimal therapy for ARVD remained uncertain until the results of the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) trial were released recently. CORAL demonstrated that optimal medical therapy was equally effective to endovascular therapy in the treatment of ARVD. Clinicians can now practice with more evidence-based medicine to treat ARVD and potentially decrease mortality in patients with ARVD using optimal medical therapy. |
Databáze: | OpenAIRE |
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