Assessment of potentially abuse-related events in two phase 3 studies of NKTR-181, a novel opioid analgesic, using the MADDERS® system (Misuse, Abuse, and Diversion Drug Event Reporting System)

Autor:	Roi Treister, Stephen K. Doberstein, Harrison Elder, Nathalie Erpelding, Nathaniel P. Katz, Ryan K. Lanier, Jack E. Henningfield, Richard Rauck, Mary Tagliaferri, Lin Lu, Suresh Siddhanti, Joseph Gimbel, Jeffrey A Gudin, Carlo J Di Fonzo
Rok vydání:	2019
Předmět:	Adult Male Drug medicine.medical_specialty media_common.quotation_subject 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Double-Blind Method medicine Humans Prospective Studies 030212 general & internal medicine Intensive care medicine Aged media_common business.industry Chronic pain Event reporting General Medicine Middle Aged Opioid-Related Disorders medicine.disease Analgesics Opioid Clinical trial Morphinans Opioid Female business Opioid analgesics Low Back Pain Reporting system Drug Accountability medicine.drug
Zdroj:	Current Medical Research and Opinion. 35:1513-1522
ISSN:	1473-4877 0300-7995
Popis:	Objective: To prospectively evaluate the abuse potential of NKTR-181, a novel opioid analgesic, in two phase 3 clinical trials using a newly developed reporting system: the Misuse, Abuse, a...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26db85a608fc17f2b8ce383af6e69fa https://doi.org/10.1080/03007995.2019.1594744 Zobrazit plný text záznamu