Nosocomial infection prevalence in patients undergoing extracorporeal membrane oxygenation (ECMO): protocol for a point prevalence study across Australia and New Zealand
| Autor: | Rachael Parke, Amanda Corley, Chris Anstey, Hergen Buscher, Vincent Pellegrino, Abhilasha Ahuja, Emma Haisz, Paul Jarrett, India Lye, Jayshree Lavana, John F. Fraser |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Prevalence 030204 cardiovascular system & hematology Young Adult 03 medical and health sciences Extracorporeal Membrane Oxygenation 0302 clinical medicine Risk Factors Protocol medicine Extracorporeal membrane oxygenation Humans Infection control Prospective Studies Child Aged Cross Infection business.industry Incidence Infection prevalence Risk of infection Australia Infant Newborn Infant 030208 emergency & critical care medicine General Medicine Middle Aged infection control Cannula Cross-Sectional Studies Infectious Diseases surgical procedures operative Child Preschool Emergency medicine Cohort Female Observational study business New Zealand |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | IntroductionExtracorporeal membrane oxygenation (ECMO) provides cardiac and/or respiratory support when other therapies fail. Nosocomial infection is reported in up to 64% of patients receiving ECMO and increases morbidity and mortality. These patients are at high risk of infection due, in part, to the multiple invasive devices required in their management, the largest being the cannulae through which ECMO is delivered. Prevalence of nosocomial infection in ECMO patients, including ECMO cannula-related infection, is not well described across Australia and New Zealand.Methods and analysisThis is a prospective, observational point prevalence study of 12 months duration conducted at 11 ECMO centres across Australia and New Zealand. Data will be collected for every patient receiving ECMO during 12 predetermined data collection weeks. The primary outcome is the prevalence of laboratory-confirmed bloodstream infection, and suspected or probable nosocomial infections; and the secondary outcomes include describing ECMO cannula dressing and securement practices, and adherence to local dressing and securement guidelines. Data collection will be finalised by March 2019.Ethics and disseminationRelevant ethical and governance approvals have been received. Study results will describe the prevalence of suspected and confirmed nosocomial infection in adult, paediatric and neonatal patients receiving ECMO across Australia and New Zealand. It is expected that the results will be hypothesis generating and lead to interventional trials aimed at reducing the high infection rates seen in this cohort. Results will be published in peer-reviewed journals and presented at relevant conferences.Trial registration numberANZCTRN12618001109291; Pre-results. |
| Databáze: | OpenAIRE |
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