Inference on microsatellite mutation processes in the invasive mite, Varroa destructor, using reversible jump Markov chain Monte Carlo
| Autor: | Michel Solignac, Arnaud Estoup, Mark A. Beaumont, Jean-Marie Cornuet |
|---|---|
| Přispěvatelé: | Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), School of Animal and Microbial Sciences, University of Reading (UOR) |
| Rok vydání: | 2006 |
| Předmět: |
0106 biological sciences
Mutation rate MCMC MICROSATELLITE DNA Mutational Analysis Locus (genetics) 010603 evolutionary biology 01 natural sciences MARKOV CHAIN MONTE CARLO 03 medical and health sciences symbols.namesake Animals Allele abeille domestique Ecology Evolution Behavior and Systematics 030304 developmental biology [SDV.EE]Life Sciences [q-bio]/Ecology environment Genetics Mites 0303 health sciences Models Genetic Markov chain biology [SDV.BA]Life Sciences [q-bio]/Animal biology Reproduction Markov chain Monte Carlo VARROA DESTRUCTOR Bees Reversible-jump Markov chain Monte Carlo biology.organism_classification Markov Chains Europe INSECTE Varroa destructor symbols Microsatellite Female MUTATION MODEL GENETIQUE DES POPULATIONS Monte Carlo Method Microsatellite Repeats |
| Zdroj: | Theoretical Population Biology Theoretical Population Biology, Elsevier, 2006, 69, pp.129-144 Theoretical Population Biology, Elsevier, 2006, 69 (2), pp.129-144. ⟨10.1016/j.tpb.2005.07.005⟩ |
| ISSN: | 0040-5809 1096-0325 |
| DOI: | 10.1016/j.tpb.2005.07.005 |
| Popis: | Correspondance : jmcornuet@supagro.inra.fr; International audience; Varroa destructor is a parasitic mite of the Eastern honeybee Apis cerana. Fifty years ago, two distinct evolutionary lineages (Korean and Japanese) invaded the Western honeybee Apis mellifera. This haplo–diploid parasite species reproduces mainly through brother–sister matings, a system which largely favors the .xation of new mutations. In a worldwide sample of 225 individuals from 21 locations collected on Western honeybees and analyzed at 19 microsatellite loci, a series of de novo mutations was observed. Using historical data concerning the invasion, this original biological system has been exploited to compare three mutation models with allele size constraints for microsatellite markers: stepwise (SMM) and generalized (GSM) mutation models, and a model with mutation rate increasing exponentially with microsatellite length (ESM). Posterior probabilities of the three models have been estimated for each locus individually using reversible jump Markov Chain Monte Carlo. The relative support of each model varies widely among loci, but the GSM is the only model that always receives at least 9% support, whatever the locus. The analysis also provides robust estimates of mutation parameters for each locus and of the divergence time of the two invasive lineages (67,000 generations with a 90% credibility interval of 35,000–174,000). With an average of 10 generations per year, this divergence time .ts with the last post-glacial Korea–Japan land separation |
| Databáze: | OpenAIRE |
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