The association between increased maternal PARK7 (DJ-1) levels and the occurrence of preterm premature rupture of membranes - A randomized prospective study

Autor:	Uğur Turhan, Burak Tatar
Rok vydání:	2021
Předmět:	DJ-1 inflammation oxidative stress Parkinson’s disease protein 7 (PARK7) Obstetrics and Gynecology Clinical Investigation Preterm premature rupture of membranes (PPROM)
Zdroj:	Turkish Journal of Obstetrics and Gynecology
ISSN:	2149-9330 1307-699X
Popis:	Objective: Parkinson’s disease protein 7 (PARK7/DJ-1) is an important antioxidant multiprotein against inflammation and oxidative stress. We therefore planned this study to demonstrate the association between maternal PARK7 levels and the occurrence of preterm premature rupture of membranes (PPROM). Materials and Methods: We enrolled 80 pregnant women; 50 PPROM patients and 30 healthy controls, into this cross- sectional study between the 24th and 36th gestational weeks. Furthermore, we measured serum PARK 7 levels using enzyme-Linked immunosorbent assay method. Results: Plasma PARK7 levels were higher in PPROM patients compared to those in the healthy controls (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2421c7c5906f4a0ab1963c32abb1100 https://doi.org/10.4274/tjod.galenos.2021.25588 Zobrazit plný text záznamu