A possible predisposition to dilated cardiomyopathy in Huntaway dogs
| Autor: | A C Hartman, C B Dyer, John S. Munday, G. M. B. Orbell |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Cardiomyopathy
Dilated Male medicine.medical_specialty Cardiomyopathy Breeding complex mixtures Dogs Risk Factors Internal medicine Prevalence Gross diagnosis Animals Medicine Genetic Predisposition to Disease Dog Diseases cardiovascular diseases General Veterinary business.industry Dilated cardiomyopathy General Medicine musculoskeletal system medicine.disease Heart failure cardiovascular system Cardiology Female business New Zealand |
| Zdroj: | New Zealand Veterinary Journal. 54:231-234 |
| ISSN: | 1176-0710 0048-0169 |
| DOI: | 10.1080/00480169.2006.36702 |
| Popis: | To compare the prevalence of dilated cardiomyopathy (DCM) in New Zealand Huntaway dogs with the prevalence of DCM in other breeds of dog.The necropsy database at Massey University was used to identify cases of DCM diagnosed between January 1999 and March 2006. Dogs were considered to have DCM if echocardiographic, gross necropsy, or histological findings were consistent with this diagnosis. The prevalence in Huntaways was then compared with the prevalence observed in all breeds of dog, as well as the prevalence observed in large breeds of dog.Twelve dogs were identified with DCM. One was diagnosed using echocardiography, while the other 11 were diagnosed by gross necropsy examination. The gross diagnosis of DCM was confirmed histologically in 6/11 dogs. The prevalence of DCM in Huntaways was significantly higher than the prevalence seen in all breeds of dog (p=0.008), and the prevalence in large breeds of dog (p=0.025). All four Huntaways diagnosed with DCM were male, and had an average age of 4 years. Three dogs presented with symptoms attributable to impaired heart function while one presented with symptoms of chronic renal failure. The duration of clinical symptoms prior to presentation ranged between 1 day and 3 weeks.The results of this study suggest that Huntaways may be predisposed to the development of DCM. Although the increased prevalence in this breed was significant, only small numbers of affected Huntaways were identified, and additional cases are required to confirm these preliminary findings.Huntaways are the most common working dog in New Zealand. The premature loss of a working dog is expected to have a significant economic impact on farmers. Further investigation of DCM in Huntaways may allow measures to reduce the prevalence in this breed. |
| Databáze: | OpenAIRE |
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