Comparison of transradial and transfemoral coronary intervention in octogenarians with acute myocardial infarction

Autor: Jung Cheon Choi, Myung Ho Jeong, Kwang Soo Cha, Hye Yoon Jang, Youngkeun Ahn, Jong Hyun Choi, Shung Chull Chae, Jun-Hyok Oh, Young Jo Kim, Hye Won Lee, Jinhee Ahn, Jung Hyun Choi, Han Cheol Lee, Taek Jong Hong, Eun-Young Yun
Rok vydání: 2014
Předmět:
Zdroj: International journal of cardiology. 202
ISSN: 1874-1754
Popis: Background The transradial (TR) approach for percutaneous coronary intervention (PCI) is challenging and associated with failure in elderly patients. We compared the TR and transfemoral (TF) approaches in patients >80years with acute myocardial infarction (MI) undergoing PCI. Methods A total of 1945 (7.2%) octogenarians were enrolled from among 27,129 patients in the Korea Acute Myocardial Infarction Registry. The TR group (n=336, 17.3%) was compared with the TF group (n=1609, 82.7%) in the overall and propensity-matched cohorts with respect to procedural success, complications, in-hospital mortality, and one-year mortality and total major adverse cardiac event (MACE; death, MI, and revascularization) rate. Results In the overall cohort, the TR group had lower incidence of Killip class III or IV compared to the TF group. The disease extent and lesion severity were similar between groups, as was the procedural success rate (97.7% vs. 98.3%); however, in-hospital complications were significantly lower in the TR group (8.1% vs. 20.3%). In-hospital mortality was significantly lower in the TR group than the TF group (3.4% vs. 11.4%), as were the one-year mortality and total MACE (9.8% vs. 18.4% and 13% vs. 21.9%, respectively). These outcomes were consistent in the propensity-matched cohort. The TR approach was found to be a significant predictor of low in-hospital mortality (OR 0.355, 95% CI 0.139–0.907), but not of one-year mortality (OR 0.644, 95% CI 0.334–1.240). Conclusions In octogenarians with acute MI undergoing PCI, the TR approach was more effective than the TF approach as it had lower complication rate and better clinical outcomes with comparable procedural success.
Databáze: OpenAIRE