Predicting anemia using NIR spectrum of spent dialysis fluid in hemodialysis patients
| Autor: | Branislava Jeftić, Jasna Trbojević-Stanković, Lidija Matija, Valentina Matovic |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Erythrocyte Indices
medicine.medical_specialty Anemia Science 030232 urology & nephrology 030204 cardiovascular system & hematology Hematocrit Gastroenterology Article 03 medical and health sciences Hemoglobins 0302 clinical medicine Total iron-binding capacity Renal Dialysis Internal medicine hemic and lymphatic diseases medicine Humans Mean corpuscular volume Monitoring Physiologic Multidisciplinary Spectroscopy Near-Infrared medicine.diagnostic_test Mean corpuscular hemoglobin concentration biology Anemia Iron-Deficiency business.industry Transferrin saturation medicine.disease Computational biology and bioinformatics Ferritin Nephrology biology.protein Quality of Life Medicine Hemoglobin business circulatory and respiratory physiology |
| Zdroj: | Scientific Reports Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021) |
| ISSN: | 2045-2322 |
| Popis: | Anemia is commonly present in hemodialysis (HD) patients and significantly affects their survival and quality of life. NIR spectroscopy and machine learning were used as a method to detect anemia in hemodialysis patients. The aim of this investigation has been to evaluate the near-infrared spectroscopy (NIRS) as a method for non-invasive on-line detection of anemia parameters from HD effluent by assessing the correlation between the spectrum of spent dialysate in the wavelength range of 700–1700 nm and the levels of hemoglobin (Hb), red blood cells (RBC), hematocrit (Hct), iron (Fe), total iron binding capacity (TIBC), ferritin (FER), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) in patient blood. The obtained correlation coefficient (R) for RBC was 0.93, for Hb 0.92, for Fe 0.94, for TIBC 0.96, for FER 0.91, for Hct 0.94, for MCV 0.92, for MCHC 0.92 and for MCH 0.93. The observed high correlations between the NIR spectrum of the dialysate fluid and the levels of the studied variables support the use of NIRS as a promising method for on-line monitoring of anemia and iron saturation parameters in HD patients. |
| Databáze: | OpenAIRE |
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