The influence of external environment fluctuations on the signal formation of microbiosensors
| Autor: | A.L. Simonian, V.B. Arakelian, James R. Wild |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Stochastic Processes
Chemistry Biomedical Engineering Biophysics Analytical chemistry Spectral density Biosensing Techniques General Medicine Function (mathematics) Models Theoretical Sensitivity and Specificity Signal Correlation function (statistical mechanics) Dispersion (optics) Electrochemistry Current (fluid) Electric current Biological system Biosensor Biotechnology |
| Zdroj: | Biosensors and Bioelectronics. 16:69-72 |
| ISSN: | 0956-5663 |
| DOI: | 10.1016/s0956-5663(00)00127-5 |
| Popis: | This part of theoretical analysis describes the fluctuations of output signal of microbiosensors when the number of accessible molecular recognition elements (enzymes, receptors, antibodies, etc.) fluctuated under external environmental influences. The mean electric current, dispersion correlating function, as well as spectral density of output current fluctuation are analyzed, and it is shown that a comparison of theoretically calculated mean current and correlation function with experimental data allow a determination of the kinetic parameters of substrate binding reaction with the molecular recognition element of biosensor. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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