[Drug and herbal hepatotoxicity: an overview of clinical classifications]
| Autor: | Mária Szántová, Martina Jakabovičová, Jozef Sedlačko |
|---|---|
| Jazyk: | čeština |
| Rok vydání: | 2018 |
| Předmět: |
Drug
medicine.medical_specialty Injury control Accident prevention media_common.quotation_subject Herbal Medicine Poison control Suicide prevention Occupational safety and health 03 medical and health sciences 0302 clinical medicine Risk Factors Injury prevention Internal Medicine medicine Humans Intensive care medicine media_common business.industry Human factors and ergonomics Liver Failure Acute 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female Chemical and Drug Induced Liver Injury Cardiology and Cardiovascular Medicine business |
| Zdroj: | Vnitrni lekarstvi. 64(4) |
| ISSN: | 0042-773X |
| Popis: | Drug induced liver injury (DILI) is often underdiagnosed disease with increasing incidence. In developed countries it belongs to the leading causes of acute liver failure. Risk groups are women and persons older than 60 years. The work summarizes the up to date information on diagnosis and mostly used classifications on DILI. It is quite often and serious complication of medicament therapy. DILI belongs to the most often cause of acute hepatic failure in the old age in developed countries. Diagnostic procedure includes medical history (time correlation with drug intake), clinical symptoms and blood tests. Laboratory tests may be helpful to specify immunopathogenetic origin, but negative results does not exclude diagnosis. The exclusion of other possible etiological factors is the crucial condition of diagnosis statement. Key words: DILI/drug induced liver toxicity - DILIn network - RUCAM classification. |
| Databáze: | OpenAIRE |
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