Determination of calcium and parathyroid hormone levels following hemithyroidectomy
| Autor: | Cristina Fernández Martínez, Isabel Fernández Palop, María Jesús Segura Giménez, M Carmen Azorin Samper, Rafael García Fuster |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism 030232 urology & nephrology Urology Parathyroid hormone chemistry.chemical_element 030209 endocrinology & metabolism Thyroid Lobectomy Calcium Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine Endocrinology Hemithyroidectomy Medicine Hypocalcaemia Intraoperative PTH Prospective cohort study Calcium metabolism Hypocalcemia Endocrine and Autonomic Systems business.industry Research Thyroid Ionised calcium medicine.disease RC648-665 medicine.anatomical_structure chemistry business |
| Zdroj: | Thyroid Research Thyroid Research, Vol 14, Iss 1, Pp 1-6 (2021) |
| ISSN: | 1756-6614 |
| Popis: | Background and objective Hypocalcemia is one of the main complications of thyroid surgery. We hypothesized that hemithyroidectomy may have an impact on serum parathyroid hormone (PTH) and calcium levels despite only one thyroid lobe is manipulated. The objective of this study was to analyze changes in serum PTH and calcium levels following hemithyroidectomy. Methods This is a prospective study of 53 patients who underwent thyroid lobectomy. The serum PTH level was determined in the preoperative period, 15 min after extraction of the surgical specimen, and 24 h and 3 weeks after surgery. Serum ionized calcium was also measured in the preoperative period and at 6 h, 24 h and 3 weeks after surgery. We assessed the postoperative calcium value and its relationship with the extent of fall in PTH levels in the postoperative period. Results None of the patients had the postoperative serum ionised calcium level less than 4 mg/dl. The decrease in postoperative calcium was statistically significant at 6 and 24 h after surgery; there was no difference at 3 weeks post-surgery. The change in post-operative serum PTH levels followed a similar trend to postoperative serum calcium levels. Conclusions Although serum calcium level decreased after a lobectomy, it always remained above 4 mg/dl. We conclude that hypocalcaemia is rare following hemithyroidectomy. |
| Databáze: | OpenAIRE |
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