BMI is Associated with Coronavirus Disease 2019 Intensive Care Unit Admission in African Americans
| Autor: | Jerry S Zifodya, Jonah S Kreniske, Vivian Fonseca, John J. Lefante, Joseph A. Lasky, Joanna Khatib, Christine M. Bojanowski, Ala Alkhatib, Mohammad Tahboub, Joshua L. Denson |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Endocrinology Diabetes and Metabolism Pneumonia Viral Medicine (miscellaneous) 030209 endocrinology & metabolism Disease Severity of Illness Index Body Mass Index law.invention Betacoronavirus 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors law Internal medicine Severity of illness Pandemic Odds Ratio medicine Humans 030212 general & internal medicine Pandemics Aged Retrospective Studies Nutrition and Dietetics SARS-CoV-2 business.industry COVID-19 Retrospective cohort study Odds ratio Middle Aged Intensive care unit Black or African American Hospitalization Intensive Care Units Cross-Sectional Studies Commentary Female Coronavirus Infections business Body mass index |
| Zdroj: | Obesity (Silver Spring, Md.) Obesity |
| ISSN: | 1930-739X 1930-7381 |
| Popis: | Objective Coronavirus disease 2019 (COVID-19) has disproportionately impacted the African American community. This study aims to identify the risk factors for severe COVID-19 disease in African American patients. Methods This was a retrospective cross-sectional analysis of African American patients with COVID-19 treated between March 12 and April 9, 2020, at a single tertiary center. The primary outcome of interest was severe disease defined as those requiring intensive care unit (ICU) admission. Results The study included 158 consecutive patients. The mean age was 57 years, and 61% were women. The mean (SD) of BMI was 33.2 (8.6) kg/m2 . Overall, patients admitted to the ICU were older (62 vs. 55 years, P = 0.003) and had higher BMI (36.5 kg/m2 vs. 31.9 kg/m2 , P = 0.002). In unadjusted and adjusted analysis, the factors most associated with ICU admission in this sample were age (adjusted odds ratio [aOR]: 1.073; 95% CI: 1.033-1.114), BMI (aOR: 1.115; 95% CI: 1.052-1.182), and lung disease (aOR: 3.097; 95% CI: 1.137-8.437). Conclusions This study identified risk factors for severe disease in COVID-19, specifically in an African American population. Further inclusive research aimed at optimizing clinical care relevant to the African American population is critical to ensure an equitable response to COVID-19. |
| Databáze: | OpenAIRE |
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