Nucleotide Sequence of Rat Steroidogenic Acute Regulatory Protein Complementary DNA
| Autor: | Hye Kyung Lee, Hyuk-Bang Kwon, Ryun S. Ahn, Jaemog Soh |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
DNA Complementary Trophic hormone Genetic Vectors Molecular Sequence Data Biophysics Clone (cell biology) Biology Biochemistry Mice Protein sequencing Complementary DNA Testis Animals Amino Acid Sequence Cloning Molecular Molecular Biology Peptide sequence chemistry.chemical_classification Base Sequence Steroidogenic acute regulatory protein Nucleic acid sequence Cell Biology Phosphoproteins Molecular biology Rats Amino acid Gene Expression Regulation chemistry Organ Specificity COS Cells Female |
| Zdroj: | Biochemical and Biophysical Research Communications. 230:528-532 |
| ISSN: | 0006-291X |
| Popis: | The steroidogenic acute regulatory (StAR) protein is a key regulator for the steroidogensis in acute response to trophic hormone. A rat complementary DNA of the StAR protein was cloned and its complete nucleotide sequence was determined.2The deduced amino acid sequence of the clone has an additional 86 amino acid stretch at amino terminus when it was compared with those sequences in other species. The other part of the amino acid sequence has 94% identity to mouse StAR protein sequence. Three transcripts (1.3 kb, 1.6 kb, and 3.5 kb) which are hybridizing to the clone were detected in testis, ovary and adrenal gland. When the cDNA was expressed in COS1 cells, 30 kDa and 47 kDa proteins specific to the anti-StAR antibody were detected. |
| Databáze: | OpenAIRE |
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