Synthesis of substituted pyrazoles via tandem cross-coupling/electrocyclization of enol triflates and diazoacetates

Autor:	Raymond Still, David J. Babinski, Doug E. Frantz, Hector R. Aguilar
Rok vydání:	2011
Předmět:	Coupling chemistry.chemical_classification Diazonium Compounds Tandem Molecular Structure Stereochemistry Organic Chemistry Stereoisomerism Combinatorial chemistry Enol Catalysis Article chemistry.chemical_compound Cross-Linking Reagents chemistry Cyclization Molecule Pyrazoles
Zdroj:	The Journal of organic chemistry. 76(15)
ISSN:	1520-6904
Popis:	The synthesis of 3,4,5-trisubstituted pyrazoles via a tandem catalytic cross-coupling/electrocyclization of enol triflates and diazoacetates is presented. The initial scope of this methodology is demonstrated on a range of differentially substituted acyclic and cyclic enol triflates as well as an elaborated set of diazoacetates to provide the corresponding pyrazoles with a high degree of structural complexity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21e23f4b957a14505fded4b971fad25 https://pubmed.ncbi.nlm.nih.gov/21682322 Zobrazit plný text záznamu