A framework for the systematic consideration of ethics, equity, feasibility, and acceptability in vaccine program recommendations

Autor: Kendra Hardy, Kelsey Young, Nadine Sicard, Caroline Quach, Matthew Tunis, Shainoor J. Ismail
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Process management
SAGE
Strategic Advisory Group of Experts
Computer science
Religion
Education
Socioeconomic status
and Social capital
P2ROGRESS And Other Factors
Pre-existing condition
Place of residence
Race/ethnicity/culture/language/immigrant/refugee status
Occupation
Gender identity/sex
Religion/belief system
Education
Socioeconomic status
Social capital
Age and Other factors (e.g. risk behaviours)
ACIP
Advisory Committee on Immunization Practices
United States
0302 clinical medicine
Acceptability
RZV
Recombinant Zoster Vaccine
NACI
National Advisory Committee on Immunization
030212 general & internal medicine
Vaccines
PHN
Post-Herpetic Neuralgia
Stakeholder
Feasibility
Equity
EEFA
Ethics
Equity
Feasibility
Acceptability
PROGRESS
Place of residence
Race/ethnicity/culture/language
Occupation
Gender/sex
Infectious Diseases
Systematic review
Molecular Medicine
Public Health
HZ
Herpes Zoster
Canada
2019-20 coronavirus outbreak
medicine.medical_specialty
ACS
Advisory Committee Statement
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
030231 tropical medicine
Framework
VPD
Vaccine-Preventable Disease
EtD
Evidence to Decision
Article
WHO
World Health Organization
03 medical and health sciences
medicine
Relevance (information retrieval)
Ethics
General Veterinary
General Immunology and Microbiology
ComputingMilieux_THECOMPUTINGPROFESSION
CCDPHE
Centre for Chronic Disease Prevention and Health Equity
Immunization Programs
Public health
LZV
Live Zoster Vaccine
Critical factors
Vaccine Program
Public Health
Environmental and Occupational Health
Equity (finance)
NITAG
National Immunization Technical Advisory Group
PHAC
Public Health Agency of Canada
PHECG
Public Health Ethics Consultative Group
CIC
Canadian Immunization Committee
Feasibility Studies
CIG
Canadian Immunization Guide
GRADE
Grading of Recommendations Assessment
Development and Evaluation
Zdroj: Vaccine
ISSN: 1873-2518
0264-410X
Popis: Highlights • Practical, evidence-informed advice considers the spectrum of public health science. • This framework fills a gap in the comprehensive development of vaccine guidance. • It enables the systematic examination of ethics, equity, feasibility, and acceptability. • In Canada, successful implementation has led to timely, transparent recommendations. • These tools, based on extensive research, can be used by advisory groups worldwide.
For the successful implementation of population-level recommendations, it is critical to consider the full spectrum of public health science, including clinical and programmatic factors. Current frameworks may identify various factors that should be examined when making evidence-informed vaccine-related recommendations. However, while most immunization guidelines systematically assess clinical factors, such as efficacy and safety of vaccines, there is no published framework outlining how to systematically assess programmatic factors, such as the ethics, equity, feasibility, and acceptability of recommendations. We have addressed this gap with the development of the EEFA (Ethics, Equity Feasibility, Acceptability) Framework, supported by evidence-informed tools, including Ethics Integrated Filters, Equity Matrix, Feasibility Matrix, and an Acceptability Matrix. The Framework and tools are based on five years of environmental scans, systematic reviews and surveys, and refined by expert and stakeholder consultations and feedback. For each programmatic factor, the EEFA Framework summarizes the minimum threshold for consideration and when further in-depth analysis may be required, which aspects of the factor should be considered, how to assess the factor using the supporting evidence-informed tools, and who should be consulted to complete the assessment. Research, particularly in the fields of vaccine acceptability and equity, has validated the utility and comprehensiveness of the tools. The Framework has been successfully used in Canada for clear, timely, transparent vaccine guidance with positive stakeholder feedback on its comprehensiveness, relevance and appropriateness. Applying the EEFA Framework allows for the systematic consideration of the spectrum of public health science without a delay in recommendations, complementing existing decision-making frameworks. This Framework will therefore be useful for advisory groups worldwide to integrate critical factors that could impact the successful and timely implementation of comprehensive, transparent recommendations, and will further the global objective of developing practical and evidence-informed immunization policies.
Databáze: OpenAIRE
Externí odkaz: