Histopathological Findings in Clinical Gentamicin Ototoxicity
| Autor: | Hugh O. Barber, Malcolm Keene, Joseph Farkashidy, Michael Hawke |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Pathology
medicine.medical_specialty Hearing loss Hearing Loss Sensorineural Ear Middle Nephrectomy Basal (phylogenetics) Ototoxicity Renal Dialysis Vertigo Temporal bone otorhinolaryngologic diseases Humans Medicine Cochlea biology business.industry Temporal Bone General Medicine Anatomy Middle Aged biology.organism_classification medicine.disease Neuroepithelial cell Otorhinolaryngology Ear Inner Female Surgery Gentamicin Vestibule Labyrinth sense organs Gentamicins medicine.symptom business medicine.drug |
| Zdroj: | Archives of Otolaryngology - Head and Neck Surgery. 108:65-70 |
| ISSN: | 0886-4470 |
| DOI: | 10.1001/archotol.1982.00790500001001 |
| Popis: | • The temporal bone histopathological findings in a case of gentamicin sulfateinduced hearing loss and vertigo in an anephric patient undergoing hemodialysis are presented. A study of the sensory neuroepithelium of the cristae and maculae disclosed the presence of vacuoles with clubbing of the sensory cells. In the cochlea, loss of the innermost row of outer hair cells in the basal turn was the most prominent feature. These findings are discussed in light of reports of similar morphological changes in laboratory studies of gentamicin ototoxicity. ( Arch Otolaryngol 1982;108:65-70) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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