Predictive value of oxidative, antioxidative, and inflammatory status for left ventricular systolic recovery after percutaneous coronary intervention for ST-segment elevation myocardial infarction

Autor:	Fatih Aksoy, Hasan Aydin Baş, Ali Bağcı, Hasan Basri Savaş, Mehmet Özaydın
Rok vydání:	2022
Předmět:	Myocardial Infarction Stroke Volume General Medicine Oxidants Ventricular Function Left Antioxidants Oxidative Stress C-Reactive Protein Percutaneous Coronary Intervention ST elevation myocardial infarction Humans ST Elevation Myocardial Infarction Ventricular dysfunction
Zdroj:	Revista da Associação Médica Brasileira v.68 n.10 2022 Revista da Associação Médica Brasileira Associação Médica Brasileira (AMB) instacron:AMB
ISSN:	1806-9282 0104-4230
Popis:	SUMMARY OBJECTIVE: This study aimed to evaluate the association between left ventricular ejection fraction recovery and the total oxidant status, total antioxidant capacity, and high-sensitivity C-reactive protein levels. METHODS: A total of 264 ST-elevation myocardial infarction patients were classified into two groups according to baseline and 6-month follow-up left ventricular systolic function: reduced and recovery systolic function. Predictors of the recovery of left ventricular ejection fraction were determined by multivariate regression analyses. RESULTS: Multivariable analysis indicated that oxidative status index, baseline left ventricular ejection fraction and peak creatine-kinase myocardial bundle level, and high-sensitivity C-reactive protein were independently associated with the decreased of left ventricular ejection fraction at 6-month follow-up. CONCLUSION: Oxidative stress and inflammation parameters were detrimental to the recovery of left ventricular ejection fraction in patients with ST-elevation myocardial infarction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2138b1e953c83106cfcbdb573121349 https://doi.org/10.1590/1806-9282.20220300 Zobrazit plný text záznamu