Effect of supplementation with the reduced form of coenzyme Q10 on semen quality and antioxidant status in dogs with poor semen quality: three case studies
| Autor: | Kanako Ueno, Tatsuya Hori, Eiichi Kawakami, Yume Yamashita, Hinano Tsuchiya, Marika Kobayashi, Moe Onozawa, Masanori Kobayashi, Masato Kobayashi, Chie Tsuzuki |
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| Rok vydání: | 2021 |
| Předmět: |
Male
endocrine system Ubiquinol antioxidant Antioxidant Ubiquinone medicine.medical_treatment canine macromolecular substances medicine.disease_cause Antioxidants Male infertility Andrology Semen quality chemistry.chemical_compound Dogs semen quality Semen coenzyme Q10 medicine Animals Sperm motility Coenzyme Q10 General Veterinary urogenital system business.industry Note medicine.disease Spermatozoa superoxide dismutase Sperm Semen Analysis chemistry Dietary Supplements Sperm Motility Theriogenology business Oxidative stress |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.21-0174 |
| Popis: | Oxidative stress owing to an imbalance between reactive oxygen species and antioxidants, such as coenzyme Q10 (CoQ10), is a major contributor to male infertility. We investigated the effects of the reduced form of CoQ10 (ubiquinol) supplementation on semen quality in dogs with poor semen quality. Three dogs received 100 mg of ubiquinol orally once daily for 12 weeks. Semen quality, serum testosterone, and seminal plasma superoxide dismutase (SOD) activity were examined at 2-week intervals from 2 weeks before ubiquinol supplementation to 4 weeks after the treatment. Ubiquinol improved sperm motility, reduced morphologically abnormal sperm, and increased seminal plasma SOD activity; however, it had no effect on testosterone level, semen volume, and sperm number. Ubiquinol supplementation could be used as a non-endocrine therapy for infertile dogs. |
| Databáze: | OpenAIRE |
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