Community acquired pneumonia in diabetic and non-diabetic hospitalized patients: presentation, causative pathogens and outcome
| Autor: | S H Z Rahman, N H Sikder, K N Uddin, M J Islam, S A Begum, L Nishat, M A A Saibal |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Pleural effusion Comorbidity Microbial Sensitivity Tests Drug resistance medicine.disease_cause law.invention Diabetes Complications Community-acquired pneumonia law Drug Resistance Multiple Bacterial Internal medicine Diabetes mellitus Streptococcus pneumoniae Diabetes Mellitus Pneumonia Bacterial Humans Medicine Prospective Studies Intensive care medicine Bangladesh business.industry Sputum General Medicine Middle Aged medicine.disease Intensive care unit Anti-Bacterial Agents Community-Acquired Infections Pleural Effusion Klebsiella pneumoniae Pneumonia Case-Control Studies Female business |
| Zdroj: | Bangladesh Medical Research Council Bulletin. 38:98-103 |
| ISSN: | 2224-7238 0377-9238 |
| DOI: | 10.3329/bmrcb.v38i3.14336 |
| Popis: | Both community acquired pneumonia and diabetes mellitus are common in Bangladesh. Though hospitalization of diabetic patients with CAP is increasing, data regarding their clinical presentation, microbial characteristics, antimicrobial susceptibility and outcome are lacking. This study was aimed at finding any difference in clinical presentation, bacterial causes, antimicrobial susceptibility pattern of isolated bacteria and outcome in diabetic and non-diabetic hospitalized patients with CAP. In this study total 47 diabetic and 43 non-diabetic adult hospitalized patients with CAP were enrolled. Clinical presentation of CAP differed in diabetics and non-diabetics. Frequency of atypical presentation and CURB-65 score were significantly higher in diabetics. Pleural effusion with multilobar infiltration was also common feature for CAP in diabetic patients. Klebsiella pneumoniae was the most frequent causative pathogen for CAP in diabetic patients, whereas Streptococcus pneumoniae was the most frequent causative agent for non-diabetic patients. Bacteria isolated from sputum sample of diabetic patients with CAP were resistant to almost all recommended antibiotics used for CAP but 100% of isolates were sensitive to Carbapenems. Pulmonary complications were relatively more in diabetics than in non-diabetics. Hospitalized diabetics with CAP required referral to intensive care unit more than that of non-diabetics. So, diabetic patients with CAP need extra attention. DOI: http://dx.doi.org/10.3329/bmrcb.v38i3.14336 Bangladesh Med Res Counc Bull 2012; 38(3): 98-103 (December) |
| Databáze: | OpenAIRE |
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