Developmental and morphological studies in Japanese medaka with ultra-high resolution optical coherence tomography
| Autor: | Barry Cense, Toyohiko Yatagai, Masaru Matsuda, Boaz Jessie Jackin, Fanny Moses Gladys, Yiheng Lim, Takuto Imai, Yukitoshi Otani |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty animal structures medicine.diagnostic_test fungi Resolution (electron density) Japanese Medaka Lateral resolution Biology Ultra high resolution Article Atomic and Molecular Physics and Optics Cell biology law.invention Optical coherence tomography Confocal microscopy law embryonic structures medicine Fish Biotechnology |
| Zdroj: | Biomedical Optics Express. 6:297 |
| ISSN: | 2156-7085 |
| Popis: | We propose ultra-high resolution optical coherence tomography to study the morphological development of internal organs in medaka fish in the post-embryonic stages at micrometer resolution. Different stages of Japanese medaka were imaged after hatching in vivo with an axial resolution of 2.8 µm in tissue. Various morphological structures and organs identified in the OCT images were then compared with the histology. Due to the medaka's close resemblance to vertebrates, including humans, these morphological features play an important role in morphogenesis and can be used to study diseases that also occur in humans. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|