Effect of circadian rhythm type on serum lipid levels in shift workers: A 5-year cohort study
| Autor: | Kouichi Sakata, Kumihiko Tanaka, Aki Tomizawa, Yuuka Watanabe, Kazuhiro Nogawa, Mitsuhiro Oishi, Yasushi Suwazono |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Physiology 030209 endocrinology & metabolism Shift work Cohort Studies 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Physiology (medical) Internal medicine Surveys and Questionnaires Work Schedule Tolerance Linear regression Medicine Humans Circadian rhythm Morning business.industry Cholesterol Middle Aged Lipids Confidence interval Circadian Rhythm chemistry Female business Sleep 030217 neurology & neurosurgery Cohort study Lipoprotein |
| Zdroj: | Chronobiology international. 36(6) |
| ISSN: | 1525-6073 |
| Popis: | We investigated how differences in circadian rhythm type affect the health of workers engaged in shift work. Employees, who were newly hired in a steel company between 2007 and 2011, received the Morningness-Eveningness Questionnaire (MEQ) survey. The target participants were 153 male shift workers who were not being treated with any antihyperlipidemic drugs and underwent periodic physical examinations including blood tests at least twice. According to the score of the MEQ at the time of joining the company, we classified the subjects into five types. Longitudinal changes in serum lipid level were estimated among the circadian rhythm types adjusted for age, BMI, and other covariates using a linear mixed model. The regression coefficient of total cholesterol level in the "definitely and moderately morning" group was -17.83 (95% confidence interval (CI): -33.42 to -2.23), and in the "intermediate 'group' was -16.84 [95% CI: -30.40 to -3.28], compared to the moderate evening type." The total cholesterol level was higher in the moderately evening type than in any of the other groups. Between the Morningness-Eveningness (ME) type and Low-density lipoprotein (LDL) cholesterol levels, compared with the "moderately evening type" group, the regression coefficient in the "intermediate type" group was -16.08 (95% CI: -28.79 to -3.37), and in the "definitely and moderately morning type" group was -17.50 [95% CI: -32.11 to -2.88]. The "moderately evening type" group had a higher LDL cholesterol level than any of the other groups. Evening-type circadian rhythm type shift workers are more prone to elevated serum lipid levels. |
| Databáze: | OpenAIRE |
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