Mechanism underlying liquid-to-solid phase transition in fused in sarcoma liquid droplets

Autor:	Shujie Li, Takuya Yoshizawa, Yutaro Shiramasa, Mako Kanamaru, Fumika Ide, Keiji Kitamura, Norika Kashiwagi, Naoya Sasahara, Soichiro Kitazawa, Ryo Kitahara
Rok vydání:	2022
Předmět:	Amyotrophic Lateral Sclerosis General Physics and Astronomy Humans RNA-Binding Protein FUS Sarcoma Physical and Theoretical Chemistry Arginine Phase Transition Aged
Zdroj:	Physical chemistry chemical physics : PCCP. 24(32)
ISSN:	1463-9084
Popis:	The liquid-to-solid phase transition of FUS liquid condensates were accelerated in the aberrant LLPS (HP-LLPS). Arginine, dopamine, and pyrocatechol suppress the formation of the aberrant LLPS more strongly than the normal LLPS (LP-LLPS).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f47bcfbf252a22253008dcfa01f25e https://pubmed.ncbi.nlm.nih.gov/35943083 Zobrazit plný text záznamu